Number of shares in issue
As at 31 December 2023, the Company has 446,679,523 Ordinary shares of £0.00001 each in issue, with 2,840,069 of these shares currently held in treasury. Based upon the remainder of issued Ordinary shares not currently held in treasury, being 443,839,454, the following interests of shareholders holding 3.0% or more are as follows:
| Significant shareholders | Origin | Holding | % |
| Invesco Limited | UK | 63,113,333 | 14.2 |
| Forward Innovation Fund | UK | 39,272,336 | 8.8 |
| Fidelity International | UK | 38,644,338 | 8.7 |
| Ruffer LLP | UK | 26,750,000 | 6.0 |
| Forward Nominees Limited | UK | 21,801,208 | 4.9 |
| Chelverton Asset Management | UK | 18,750,000 | 4.2 |
| Columbia Threadneedle | UK | 18,074,309 | 4.1 |
| GPIM | UK | 15,989,746 | 3.6 |
| BlackRock | UK | 15,100,000 | 3.4 |
| The Hargreaves No 11 Settlement | UK | 14,000,000 | 3.2 |
| NFU Mutual | UK | 13,841,465 | 3.1 |
In accordance with AIM Rule 26 in so far as the Company is aware, as at 31 December 2023 the percentage of the Company’s issued share capital that is not in public hands is 31.3%.
Details of any restrictions on the transfer of securities – There are no restrictions on the transfer of securities.
Details of any other exchange or trading platforms – The Company operates on no other exchanges or trading platforms other than AIM.